Research Interests

The Walker group studies metabolic pathways involved in microbial survival and pathogenesis with the aim of developing new approaches to overcome resistant microorganisms. The Walker laboratory also has a longstanding interest in the structure, function, and inhibition of both prokaryotic and eukaryotic glycosyltransferases. 

Approaches

Chemical Biology: the use of organic and biophysical chemistry, small molecule inhibitors, chemical probes, enzymology, molecular genetics, and cell biology to elucidate important metabolic and signaling pathways and to explore possible drug targets.